By Yvonne Connolly Martin (auth.), Hugo Kubinyi, Gerd Folkers, Yvonne C. Martin (eds.)
Significant development has been made within the examine of 3-dimensional quantitative structure-activity relationships (3D QSAR) because the first book by way of Richard Cramer in 1988 and the 1st quantity within the sequence, 3D QSAR in Drug layout. conception, tools and purposes, released in 1993. the purpose of that early booklet used to be to give a contribution to the certainty and the additional program of CoMFA and comparable techniques and to facilitate the correct use of those equipment. considering the fact that then, enormous quantities of papers have seemed utilizing the fast constructing suggestions of either 3D QSAR and computational sciences to check a huge number of organic difficulties. back the editor(s) felt that the time had come to solicit experiences on released and new viewpoints to rfile the cutting-edge of 3D QSAR in its broadest definition and to supply visions of the place new concepts will emerge or new appli- tions could be chanced on. The goal is not just to spotlight new principles but additionally to teach the shortcomings, inaccuracies, and abuses of the equipment. we are hoping this ebook will allow others to split trivial from visionary techniques and me-too method from in- vative suggestions. those issues guided our collection of individuals. To our satisfaction, our demand papers elicited an exceptional many manuscripts.
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